AX-2026-042576

L-Glutathione (reduced) · 200 mg declared · Hubei Jianxiang Bioscience Co., Ltd. · lot HJ-2511-F6153

PASSPURITY ONLY

Report ID: AX-2026-042576
Compound: L-Glutathione (reduced)
Compound class: Short bioregulator peptides
Supplier: HJ — Hubei Jianxiang Bioscience Co., Ltd.
Batch / lot: HJ-2511-F6153
Declared label claim: 200mg
Laboratory: Nordanalyt Laboratories
Assay date: 13 May 2026
Submitted: 30 May 2026
Quarter: 2026-Q2
Submitter: m.kirchner
Sample provenance: Buyer-sourced

Section 1

Results

Measured against the index acceptance specification for the short bioregulator peptides class. A specification is a decision the index made; a result is a measurement. See where each threshold came from.

Parameter	Method	Result	Unit	Index spec
Purity	RP-HPLC, 35 min gradient, 214 nm	99.79	% area	≥ 98.5	PASS
Total impurities	RP-HPLC, sum of reported peaks	0.21	% area	≤ 1.5	PASS
Largest single impurity	RP-HPLC — glutathione disulfide (GSSG, +305 Da)	0.09	% area	≤ 1.00	PASS
Identity	not ordered on this submission	not determined	—	required for VERIFIED status	NOT TESTED
Total peptide content	by difference from the gravimetric mass balance	92.54	%w/w	—	NOT TESTED
Target-compound content	total peptide content × purity	92.35	%w/w	—	NOT TESTED
Gross fill (as weighed)	five-place balance, under nitrogen	231.80	mg	200 mg declared	NOT TESTED
Recovered target peptide	gross fill × target content	214.067	mg	200 mg claim	NOT TESTED
Recovery against label claim	recovered ÷ claim	107.0	%	90.0 – 110.0	PASS
Water content	Karl Fischer, coulometric, duplicate	7.19	%	≤ 12.0	PASS
Counter-ion	no ionisable counter-ion expected	N/A	—	not applicable	NOT TESTED
Residual solvent + inorganic residue	estimated — see /methods/residual-solvents-q3c/	0.27	%	—	NOT TESTED
Endotoxin	not ordered on this submission	not determined	—	≤ 5.0	NOT TESTED
Sterility	not ordered on this submission	not determined	—	no growth	NOT TESTED
Appearance	visual, diffuse light, black and white background	Off-white lyophilised cake, intact	—	white to off-white intact cake	PASS
Reconstitution clarity	reconstituted per submitter procedure	Clear after 90 s gentle swirling, no particulates	—	clear, no visible particulates	PASS
pH (reconstituted, 1 mg/mL)	potentiometric, two-point calibration	7.63	—	2.5 – 8.0	PASS
Retention time (observed)	RP-HPLC, 35 min gradient	4.83	min	4.94 ± 0.20 (normalised)	PASS
Peak asymmetry (10 % height)	Ph. Eur. 2.2.46	0.93	—	0.80 – 1.50	PASS
Plate count, main peak	N = 5.54 (t/w½)²	73,150	—	≥ 20,000	PASS
Resolution to nearest impurity	vs S-sulfonate adduct (+80 Da)	2.23	—	no index criterion	REPORTED

Section 2

Chromatogram and peak integration

The figure is drawn from the table. It is not an independent illustration — if a number in the table changed, the trace would change with it.

Figure 1. RP-HPLC trace, 35 min gradient, 214 nm. Drawn from the peak-integration table below: peak positions are the reported retention times, peak areas are the reported area percentages, peak widths follow the reported plate count of 73,150, and skew follows the reported asymmetry factor of 0.93. Baseline noise is seeded from the report ID and is illustrative. The lower panel is the same trace at a stated vertical expansion with the slow gradient drift subtracted, because at full scale a 0.09 % impurity against a 99.79 % main peak is a line two pixels tall; the main peak runs off-scale there by design.

#	Peak	RT	Area (µV·s)	% area	Δ mass (Da)
1	L-Glutathione (reduced) — main peak	4.83	4,850,103	99.79	—
2	glutathione disulfide (GSSG, +305 Da)	5.44	4,374	0.09	+304.984
3	S-sulfonate adduct (+80 Da)	4.67	3,402	0.07	+79.957
4	γ-Glu-Cys (−57 Da)	4.62	2,430	0.05	-57.021
Closure check — purity + Σ impurities				100.00	CLOSES

Reporting threshold 0.05 % area. Peaks below it are not reported and are therefore excluded from the total, which overstates purity by their sum — see peak integration.

Section 4

Gravimetric mass balance

Water, counter-ion, residual and total peptide content are exhaustive and mutually exclusive categories. They must account for 100 % of the cake mass. The index closes this to within 0.02 pp and the build asserts it.

Component	Determination	%w/w of cake
Water	Karl Fischer	7.19
Counter-ion	none expected	0.00
Residual solvent + inorganic residue	estimated	0.27
Total peptide content	by difference	92.54
Total		100.00 CLOSES

Supplier certificate, as declared

The supplier's own figures for this lot, beside the independent measurement. Divergence is assessed against the batch median, not against this single report — see rule AX-R05.

Figure	Supplier COA	This report	Index note
Purity (% area)	99.90	99.79	divergence -0.03 pp vs batch median
Total impurities (% area)	0.10	0.21
Largest single impurity (% area)	not stated	0.09
Water (%)	4.9	7.19
Counter-ion (%)	3.1	N/A
Peptide content (%w/w)	91.4	92.54
Endotoxin (EU/mg)	not stated	not determined
Method stated on certificate	NO	—	no method section — the result cannot be reconciled against any other

Section 5

Provenance and caveats

Where a sample came from changes the weight of the evidence. The index treats it as a first-class field.

Sample provenance: Buyer-sourced
Evidentiary weight: Strongest available evidence in this index.
Chain of custody: Retail purchase → submitter (2–8 °C, 17 d) → laboratory (courier, ambient, 10 d) → assay.
Assay date: 13 May 2026
Submitted to the index: 30 May 2026
Laboratory: Nordanalyt Laboratories, Uppsala, Sweden
Method basis: 35 min gradient · high-resolution MS
Verification status: PURITY ONLY

What this report does not establish

That the compound is the compound named. No identity confirmation was ordered on this submission. A purity figure describes chromatographic homogeneity of whatever eluted; it does not name it.
That the material is free of bacterial endotoxin. Endotoxin was not measured. No chromatographic result bears on it.
That the material is sterile. Sterility was not tested.
That any other vial in the same lot has the same composition. One vial was tested. Within-lot vial-to-vial variation in this index has a median of 0.28 pp and a 90th percentile of 0.74 pp.
That any other lot from the same supplier has the same composition. Batch-to-batch variation is larger than within-batch variation for every supplier here.
That the material is suitable for administration to a human or an animal. These are research compounds. No result on this site is a safety assessment and the index takes no position on use.
That the material was manufactured by the supplier that sold it. Contract synthesis is normal in this market and twenty-nine batches in the index fingerprint to a bulk from a different company than the one named on the label.

Section 6

Annotations 2

Signed technical comments from index contributors. Not a discussion forum — annotations question or contextualise the result, and the data team replies where a reply is warranted.

cagri_disulfide30 May 2026

The index flags an open-chain fraction above a compound-specific level for cold-chain review rather than counting it against the synthesis. That handling is stated on the compound page.

thin_coverage30 May 2026

The supplier-compound cells with no endotoxin data at all are mapped on the coverage page. They are most of the matrix.

Section 7

Related records

Same batch — lot HJ-2511-F6153 n=8

Report	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Result
AX-2026-042572	HJ-2511-F6153	PeptideMeter	2026-Q2	99.93	7.33	98.3	Buyer-sourced	PASS
AX-2026-042573	HJ-2511-F6153	PeptideMeter	2026-Q2	99.93	7.65	101.8	Buyer-sourced	PASS
AX-2026-042574	HJ-2511-F6153	Janoshik	2026-Q2	99.93	7.39	—	Buyer-sourced	PASS
AX-2026-042575	HJ-2511-F6153	Janoshik	2026-Q2	99.66	7.21	—	Buyer-sourced	PASS
AX-2026-042577	HJ-2511-F6153	Kestrel	2026-Q2	99.93	6.94	—	Buyer-sourced	PASS
AX-2026-042578	HJ-2511-F6153	Janoshik	2026-Q2	99.93	7.33	—	Buyer-sourced	PASS
AX-2026-042579	HJ-2511-F6153	Nordanalyt	2026-Q2	99.93	7.10	—	Buyer-sourced	PASS

Batch rollup and reproducibility assessment →

Cross-sections

All L-Glutathione (reduced) records n=129
All HJ records n=247
All Nordanalyt records n=545
All 2026-Q2 records n=1126
L-Glutathione (reduced) by supplier
L-Glutathione (reduced) impurity profile

Other recent L-Glutathione (reduced) records in the index.
Report	Supplier	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Flags	Result
AX-2026-043429	WXT	WXT-2605-B3833	Nordanalyt	2026-Q3	98.48	6.58	96.9	Supplier-supplied	1	FAIL
AX-2026-043424	WXT	WXT-2605-B3833	PeptideMeter	2026-Q3	98.37	6.86	—	Buyer-sourced	0	FAIL
AX-2026-043166	GL Biochem	GLBI-2606-S7352	Janoshik	2026-Q3	99.01	8.84	105.4	Laboratory-retained	1	MARGINAL
AX-2026-043423	WXT	WXT-2605-B3833	Janoshik	2026-Q3	97.86	6.66	93.4	Buyer-sourced	0	FAIL
AX-2026-043426	WXT	WXT-2605-B3833	Kestrel	2026-Q3	98.83	6.32	—	Supplier-supplied	1	MARGINAL
AX-2026-043425	WXT	WXT-2605-B3833	Janoshik	2026-Q3	98.77	6.35	—	Supplier-supplied	1	MARGINAL
AX-2026-043431	WXT	WXT-2605-B3833	Nordanalyt	2026-Q3	97.94	6.18	—	Buyer-sourced	0	FAIL
AX-2026-043427	WXT	WXT-2605-B3833	Medutest	2026-Q3	97.67	6.08	—	Buyer-sourced	1	FAIL

Other recent HJ records in the index.
Report	Compound	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Flags	Result
AX-2026-042595	Semaglutide	HJ-2608-C7002	Janoshik	2026-Q3	99.50	3.55	—	Buyer-sourced	1	MARGINAL
AX-2026-042598	Semaglutide	HJ-2608-C7002	Janoshik	2026-Q3	99.59	3.84	—	Buyer-sourced	0	PASS
AX-2026-042605	Semaglutide	HJ-2608-C7002	Janoshik	2026-Q3	99.03	3.37	107.3	Buyer-sourced	0	PASS
AX-2026-042602	Semaglutide	HJ-2608-C7002	Nordanalyt	2026-Q3	99.21	3.50	92.0	Buyer-sourced	0	PASS
AX-2026-042603	Semaglutide	HJ-2608-C7002	Janoshik	2026-Q3	99.16	3.42	105.9	Buyer-sourced	0	PASS
AX-2026-042528	GHRP-6	HJ-2603-R5329	VendorInvestigate	2026-Q3	98.69	1.87	95.8	Buyer-sourced	0	FAIL
AX-2026-042526	GHRP-6	HJ-2603-R5329	Medutest	2026-Q3	99.37	3.06	—	Laboratory-retained	0	PASS
AX-2026-042527	GHRP-6	HJ-2603-R5329	VendorInvestigate	2026-Q3	99.21	2.77	93.2	Buyer-sourced	0	PASS