Cross-section

Kisspeptin-10 by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Kisspeptin-10, with a class minimum gradient of 22 min, the method is a live explanation.

76 recordsmedian 99.28 %spec 98.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	36	30min	High	99.20	+0.00	99.20	ADEQUATE
Medutest	12	25min	Unit	99.09	+0.08	99.01	ADEQUATE
PeptideMeter	9	28min	High	99.28	-0.05	99.33	ADEQUATE
Nordanalyt	8	35min	High	99.45	+0.02	99.43	ADEQUATE
VendorInvestigate	7 n=7	32min	High	99.64	-0.11	99.75	ADEQUATE
Kestrel	4 n=4	15min	Unit	99.56	+0.24	99.33	BELOW CLASS MINIMUM

Figure. Kisspeptin-10 purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.