Cross-section

CJC-1295 with DAC by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for CJC-1295 with DAC, with a class minimum gradient of 15 min, the method is a live explanation.

121 recordsmedian 98.95 %spec 97.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	60	30min	High	98.98	+0.00	98.98	ADEQUATE
PeptideMeter	21	28min	High	98.87	-0.05	98.92	ADEQUATE
Medutest	17	25min	Unit	99.09	+0.08	99.01	ADEQUATE
Nordanalyt	10	35min	High	98.94	+0.02	98.92	ADEQUATE
Kestrel	8	15min	Unit	99.11	+0.24	98.87	ADEQUATE
VendorInvestigate	5 n=5	32min	High	98.39	-0.11	98.50	ADEQUATE

Figure. CJC-1295 with DAC purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.