AssayIndex

SGN-2407-R9375

N-Acetyl Semax Amide · 20 mg declared · Sangon Biotech (Shanghai) Co., Ltd. · manufactured 12 Jul 2024

CHARACTERISED
Lot code
SGN-2407-R9375
Supplier
SGN — Sangon Biotech (Shanghai) Co., Ltd.
Compound
N-Acetyl Semax Amide
Compound class
Neuroactive and cognitive peptides
Declared label claim
20mg
Manufacture date
12 Jul 2024
Index quarter
2024-Q3
Independent assays
12
Laboratories involved
Janoshik, Medutest, VendorInvestigate, PeptideMeter, Kestrel
Provenance mix
Buyer-sourced ×10 · Supplier-supplied ×2
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 12
Median purity 98.56% n=12
Spread (max − min) 1.06pp n=12
Standard deviation 0.318pp n=12
98.198.498.799.199.499.7100.1This lot (SGN-2407-R9375)This lot (SGN-2407-R9375): Q1 98.42, median 98.56, Q3 98.76, n=12outlier 99.36n=12All N-Acetyl Semax AmideAll N-Acetyl Semax Amide: Q1 98.79, median 99.35, Q3 99.73, n=88n=88 Purity (% area)
Figure 1. This lot's independent purity results against the whole N-Acetyl Semax Amide record set in the index. The vertical line is the index acceptance specification for the neuroactive and cognitive peptides class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 12

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-005162SGN-2407-R9375Janoshik2024-Q398.818.0290.9Buyer-sourced2MARGINAL
AX-2024-005163SGN-2407-R9375Janoshik2024-Q398.368.53Buyer-sourced2FAIL
AX-2024-005164SGN-2407-R9375Medutest2024-Q398.368.36Buyer-sourced2FAIL
AX-2024-005165SGN-2407-R9375VendorInvestigate2024-Q398.748.31Buyer-sourced2MARGINAL
AX-2024-005166SGN-2407-R9375Janoshik2024-Q398.447.33106.0Buyer-sourced2FAIL
AX-2024-005167SGN-2407-R9375Janoshik2024-Q398.517.9099.6Buyer-sourced2MARGINAL
AX-2024-005168SGN-2407-R9375Janoshik2024-Q398.618.2194.5Buyer-sourced2MARGINAL
AX-2024-005169SGN-2407-R9375Janoshik2024-Q398.307.71102.5Buyer-sourced2FAIL
AX-2024-005170SGN-2407-R9375PeptideMeter2024-Q398.647.75105.2Buyer-sourced2MARGINAL
AX-2024-005171SGN-2407-R9375PeptideMeter2024-Q398.447.9096.7Supplier-supplied2FAIL
AX-2024-005172SGN-2407-R9375Janoshik2024-Q399.078.40102.9Supplier-supplied2MARGINAL
AX-2024-005173SGN-2407-R9375Kestrel2024-Q399.367.83Buyer-sourced2MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik798.81, 98.36, 98.44, 98.51, 98.61, 98.30, 99.0798.5130min+0.0098.51
Medutest198.3698.3625min+0.0898.28
VendorInvestigate198.7498.7432min-0.1198.85
PeptideMeter298.64, 98.4498.5428min-0.0598.59
Kestrel199.3699.3615min+0.2499.12

This lot contributes 10 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)98.8698.81divergence +0.30 pp vs batch median
Total impurities (% area)0.811.19
Largest single impurity (% area)1.140.49
Water (%)not stated8.02
Counter-ion (%)not stated5.06
Peptide content (%w/w)not stated86.62
Endotoxin (EU/mg)not stated0.33
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
semax (des-acetyl, des-amide, −41 Da)12 / 120.350.12–0.67
des-acetyl amide (−42 Da)12 / 120.240.08–0.44
N-acetyl semax free acid (+1 Da)12 / 120.330.19–0.68
Met sulfoxide (+16 Da)12 / 120.200.11–0.47
Section 7

What this rollup does not establish