N-Acetyl Semax Amide impurity profile
Every named species the index has reported alongside N-Acetyl Semax Amide, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
Median total impurities
0.65%
n=88
Median largest single
0.40%
n=88
Worst single observed
1.04%
n=88
Named species observed
4 / 4
n=4
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| Met sulfoxide (+16 Da) | -0.34 | +15.995 | 92% | 0.14 | 1.04 |
| semax (des-acetyl, des-amide, −41 Da) | -0.56 | -41.027 | 91% | 0.11 | 0.79 |
| des-acetyl amide (−42 Da) | -0.40 | -42.011 | 91% | 0.10 | 0.97 |
| N-acetyl semax free acid (+1 Da) | +0.22 | +0.984 | 85% | 0.18 | 1.04 |
Met sulfoxide (+16 Da)
- Retention offset from the main peak
- -0.34 min on RG-2
- Mass difference
- +15.995 Da
- Reported in
- 81 of 88 records (92 %)
- Level when reported
- median 0.14 %, max 1.04 %
- How it separates
- Baseline-resolved on the reference method.
semax (des-acetyl, des-amide, −41 Da)
- Retention offset from the main peak
- -0.56 min on RG-2
- Mass difference
- -41.027 Da
- Reported in
- 80 of 88 records (91 %)
- Level when reported
- median 0.11 %, max 0.79 %
- How it separates
- Baseline-resolved on the reference method.
des-acetyl amide (−42 Da)
- Retention offset from the main peak
- -0.40 min on RG-2
- Mass difference
- -42.011 Da
- Reported in
- 80 of 88 records (91 %)
- Level when reported
- median 0.10 %, max 0.97 %
- How it separates
- Baseline-resolved on the reference method.
N-acetyl semax free acid (+1 Da)
- Retention offset from the main peak
- +0.22 min on RG-2
- Mass difference
- +0.984 Da
- Reported in
- 75 of 88 records (85 %)
- Level when reported
- median 0.18 %, max 1.04 %
- How it separates
- Close-eluting on the reference method, and merged with the main peak on a short gradient. The index prints the resolution figure for such a pair and applies no criterion to it — where the two are not separated, what matters is that the integration convention is stated.
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- acetyl loss
- C-terminal amide hydrolysis
- Met oxidation