AssayIndex

GSP-2505-S3921

AOD-9604 · 2 mg declared · GenScript Biotech Corporation · manufactured 13 May 2025

CHARACTERISED
Lot code
GSP-2505-S3921
Supplier
GSP — GenScript Biotech Corporation
Compound
AOD-9604
Compound class
Metabolic and mitochondrial peptides
Declared label claim
2mg
Manufacture date
13 May 2025
Index quarter
2025-Q4
Independent assays
12
Laboratories involved
Janoshik, PeptideMeter, Kestrel, VendorInvestigate, Nordanalyt
Provenance mix
Buyer-sourced ×11 · Laboratory-retained ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 12
Median purity 98.60% n=12
Spread (max − min) 0.72pp n=12
Standard deviation 0.186pp n=12
98.198.498.799.199.499.7100.1This lot (GSP-2505-S3921)This lot (GSP-2505-S3921): Q1 98.46, median 98.59, Q3 98.66, n=12outlier 99.02n=12All AOD-9604All AOD-9604: Q1 98.74, median 99.29, Q3 99.49, n=96n=96 Purity (% area)
Figure 1. This lot's independent purity results against the whole AOD-9604 record set in the index. The vertical line is the index acceptance specification for the metabolic and mitochondrial peptides class, 98.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 12

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-019122GSP-2505-S3921Janoshik2025-Q498.434.1994.6Buyer-sourced0PASS
AX-2025-019123GSP-2505-S3921PeptideMeter2025-Q498.663.7192.3Buyer-sourced0PASS
AX-2025-019124GSP-2505-S3921Janoshik2025-Q498.403.79Buyer-sourced0PASS
AX-2025-019125GSP-2505-S3921PeptideMeter2025-Q498.533.47Buyer-sourced1FAIL
AX-2025-019126GSP-2505-S3921PeptideMeter2025-Q498.304.17Buyer-sourced0PASS
AX-2025-019127GSP-2505-S3921Kestrel2025-Q498.473.48Buyer-sourced0PASS
AX-2025-019128GSP-2505-S3921Janoshik2025-Q498.634.1693.7Buyer-sourced0PASS
AX-2025-019129GSP-2505-S3921VendorInvestigate2025-Q498.663.74101.6Buyer-sourced0PASS
AX-2025-019130GSP-2505-S3921VendorInvestigate2025-Q499.023.14105.7Laboratory-retained0PASS
AX-2025-019131GSP-2505-S3921VendorInvestigate2025-Q498.702.96103.8Buyer-sourced0PASS
AX-2025-019132GSP-2505-S3921Nordanalyt2025-Q498.683.54103.2Buyer-sourced0PASS
AX-2025-019133GSP-2505-S3921VendorInvestigate2025-Q498.564.0192.1Buyer-sourced0PASS
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik398.43, 98.40, 98.6398.4330min+0.0098.43
PeptideMeter398.66, 98.53, 98.3098.5328min-0.0598.58
Kestrel198.4798.4715min+0.2498.23
VendorInvestigate498.66, 99.02, 98.70, 98.5698.6832min-0.1198.79
Nordanalyt198.6898.6835min+0.0298.66

This lot contributes 10 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)98.6298.43divergence +0.02 pp vs batch median
Total impurities (% area)not stated1.57
Largest single impurity (% area)not stated1.06
Water (%)2.04.19
Counter-ion (%)not stated6.70
Peptide content (%w/w)93.288.95
Endotoxin (EU/mg)not stated0.24
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
AOD dimer12 / 120.470.23–1.15
des-Tyr AOD (−163 Da)12 / 120.310.14–0.44
open-chain (reduced disulfide, +2 Da)12 / 120.330.10–0.59
Met sulfoxide (+16 Da)12 / 120.170.08–0.23
Section 7

What this rollup does not establish