AssayIndex

GGPE-2512-Y2660

Survodutide · 15 mg declared · Nantong Guangyuan Chemical Co., Ltd. · manufactured 04 Dec 2025

CHARACTERISED
Lot code
GGPE-2512-Y2660
Supplier
GGPeps — Nantong Guangyuan Chemical Co., Ltd.
Compound
Survodutide
Compound class
Incretin analogues and co-agonists
Declared label claim
15mg
Manufacture date
04 Dec 2025
Index quarter
2026-Q2
Independent assays
14
Laboratories involved
Janoshik, Kestrel, PeptideMeter, Nordanalyt
Provenance mix
Buyer-sourced ×12 · Supplier-supplied ×1 · Laboratory-retained ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 14
Median purity 97.66% n=14
Spread (max − min) 1.31pp n=14
Standard deviation 0.368pp n=14
97.297.798.298.799.199.6100.1This lot (GGPE-2512-Y2660)This lot (GGPE-2512-Y2660): Q1 97.61, median 97.66, Q3 97.70, n=14outlier 97.37outlier 97.37outlier 97.44outlier 98.41outlier 98.68n=14All SurvodutideAll Survodutide: Q1 97.81, median 98.38, Q3 99.13, n=70n=70 Purity (% area)
Figure 1. This lot's independent purity results against the whole Survodutide record set in the index. The vertical line is the index acceptance specification for the incretin analogues and co-agonists class, 96.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 14

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042831GGPE-2512-Y2660Janoshik2026-Q297.683.56Buyer-sourced2MARGINAL
AX-2026-042832GGPE-2512-Y2660Kestrel2026-Q298.683.5992.0Laboratory-retained3FAIL
AX-2026-042833GGPE-2512-Y2660PeptideMeter2026-Q297.443.4693.3Buyer-sourced2MARGINAL
AX-2026-042834GGPE-2512-Y2660Janoshik2026-Q297.653.8788.9Buyer-sourced3MARGINAL
AX-2026-042835GGPE-2512-Y2660Janoshik2026-Q297.774.16Buyer-sourced2MARGINAL
AX-2026-042836GGPE-2512-Y2660Janoshik2026-Q297.602.83Buyer-sourced2MARGINAL
AX-2026-042837GGPE-2512-Y2660Janoshik2026-Q297.633.04Buyer-sourced2MARGINAL
AX-2026-042838GGPE-2512-Y2660Janoshik2026-Q297.693.50Buyer-sourced2MARGINAL
AX-2026-042839GGPE-2512-Y2660Janoshik2026-Q297.373.9295.0Buyer-sourced2MARGINAL
AX-2026-042840GGPE-2512-Y2660PeptideMeter2026-Q297.673.80101.8Buyer-sourced2MARGINAL
AX-2026-042841GGPE-2512-Y2660Janoshik2026-Q297.713.99Buyer-sourced2MARGINAL
AX-2026-042842GGPE-2512-Y2660Janoshik2026-Q297.634.13Buyer-sourced2MARGINAL
AX-2026-042843GGPE-2512-Y2660Nordanalyt2026-Q297.373.00Buyer-sourced2MARGINAL
AX-2026-042844GGPE-2512-Y2660Janoshik2026-Q298.414.02Supplier-supplied2MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik1097.68, 97.65, 97.77, 97.60, 97.63, 97.69, 97.37, 97.71, 97.63, 98.4197.6730min+0.0097.67
Kestrel198.6898.6815min+0.2498.44
PeptideMeter297.44, 97.6797.5628min-0.0597.61
Nordanalyt197.3797.3735min+0.0297.35

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)97.4697.68divergence -0.20 pp vs batch median
Total impurities (% area)1.632.32
Largest single impurity (% area)2.541.09
Water (%)not stated3.56
Counter-ion (%)not stated8.09
Peptide content (%w/w)91.7not determined
Endotoxin (EU/mg)0.72not determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
aspartimide (−18 Da)14 / 140.640.12–1.24
des-γGlu linker (−129 Da)14 / 140.540.15–0.97
C18 diacid mono-ester14 / 140.180.07–0.28
[D-Ser2]-diastereomer14 / 140.270.05–0.85
truncated (2-39)14 / 140.270.04–0.89
survodutide dimer14 / 140.030.02–0.06
Section 7

What this rollup does not establish