AssayIndex

AX-2026-041548

GHRP-6 · 5 mg declared · Qingdao Sigma Chemical Co., Ltd. · lot QSC-2605-A6715

MARGINALPURITY ONLY
Report ID
AX-2026-041548
Compound
GHRP-6
Compound class
Growth-hormone axis peptides
Supplier
QSC — Qingdao Sigma Chemical Co., Ltd.
Batch / lot
QSC-2605-A6715
Declared label claim
5mg
Laboratory
Janoshik Analytical
Assay date
16 May 2026
Submitted
04 Jun 2026
Quarter
2026-Q2
Submitter
y.kuusela
Sample provenance
Buyer-sourced
Section 1

Results

Measured against the index acceptance specification for the growth-hormone axis peptides class. A specification is a decision the index made; a result is a measurement. See where each threshold came from.

ParameterMethodResultUnitIndex spec
PurityRP-HPLC, 30 min gradient, 214 nm99.71% area≥ 99.0PASS
Total impuritiesRP-HPLC, sum of reported peaks0.29% area≤ 1.0PASS
Largest single impurityRP-HPLC — oxidised Trp (+16 Da)0.20% area≤ 1.00PASS
Identitynot ordered on this submissionnot determinedrequired for VERIFIED statusNOT TESTED
Total peptide contentby difference from the gravimetric mass balance89.00%w/wNOT TESTED
Target-compound contenttotal peptide content × purity88.74%w/wNOT TESTED
Gross fill (as weighed)five-place balance, under nitrogen5.00mg5 mg declaredNOT TESTED
Recovered target peptidegross fill × target content4.437mg5 mg claimNOT TESTED
Recovery against label claimrecovered ÷ claim88.7%90.0 – 110.0FAIL
Water contentKarl Fischer, coulometric, duplicate5.07%≤ 9.0PASS
Counter-ion (acetate)anion-exchange ion chromatography5.19%≤ 12.0PASS
Residual solvent + inorganic residueestimated — see /methods/residual-solvents-q3c/0.74%NOT TESTED
Endotoxinnot ordered on this submissionnot determined≤ 5.0NOT TESTED
Sterilitynot ordered on this submissionnot determinedno growthNOT TESTED
Appearancevisual, diffuse light, black and white backgroundWhite lyophilised cake, intactwhite to off-white intact cakePASS
Reconstitution clarityreconstituted per submitter procedureClear after 90 s gentle swirling, no particulatesclear, no visible particulatesPASS
pH (reconstituted, 1 mg/mL)potentiometric, two-point calibration5.172.5 – 8.0PASS
Retention time (observed)RP-HPLC, 30 min gradient8.51min8.44 ± 0.25 (normalised)PASS
Peak asymmetry (10 % height)Ph. Eur. 2.2.461.050.80 – 1.50PASS
Plate count, main peakN = 5.54 (t/w½)²53,579≥ 20,000PASS
Resolution to nearest impurityvs [D-Trp]-epimer0.80no index criterionREPORTED
Section 2

Chromatogram and peak integration

The figure is drawn from the table. It is not an independent illustration — if a number in the table changed, the trace would change with it.

030636126918912251 GHRP-68.51 min · 99.71 % 8.17 same trace · ×200 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 05101520253035 Retention time (min) Response (mAU)
Figure 1. RP-HPLC trace, 30 min gradient, 214 nm. Drawn from the peak-integration table below: peak positions are the reported retention times, peak areas are the reported area percentages, peak widths follow the reported plate count of 53,579, and skew follows the reported asymmetry factor of 1.05. Baseline noise is seeded from the report ID and is illustrative. The lower panel is the same trace at a stated vertical expansion with the slow gradient drift subtracted, because at full scale a 0.20 % impurity against a 99.71 % main peak is a line two pixels tall; the main peak runs off-scale there by design.
#PeakRTArea (µV·s)% areaΔ mass (Da)
1GHRP-6 — main peak8.514,846,21599.71
2oxidised Trp (+16 Da)8.179,7210.20+15.995
3des-Lys (−128 Da)8.291,9440.04-128.095
4bis-oxidised Trp (+32 Da)7.931,4580.03+31.990
5[D-Trp]-epimer8.399720.020.000
Closure check — purity + Σ impurities 100.00CLOSES

Reporting threshold 0.05 % area. Peaks below it are not reported and are therefore excluded from the total, which overstates purity by their sum — see peak integration.

Section 4

Gravimetric mass balance

Water, counter-ion, residual and total peptide content are exhaustive and mutually exclusive categories. They must account for 100 % of the cake mass. The index closes this to within 0.02 pp and the build asserts it.

ComponentDetermination%w/w of cake
WaterKarl Fischer5.07
Counter-ion (acetate)ion chromatography5.19
Residual solvent + inorganic residueestimated0.74
Total peptide contentby difference89.00
Total100.00 CLOSES

Supplier certificate, as declared

The supplier's own figures for this lot, beside the independent measurement. Divergence is assessed against the batch median, not against this single report — see rule AX-R05.

FigureSupplier COAThis reportIndex note
Purity (% area)99.7299.71divergence -0.04 pp vs batch median
Total impurities (% area)0.280.29
Largest single impurity (% area)0.150.20
Water (%)not stated5.07
Counter-ion (%)not stated5.19
Peptide content (%w/w)91.789.00
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Provenance and caveats

Where a sample came from changes the weight of the evidence. The index treats it as a first-class field.

Sample provenance
Buyer-sourced
Evidentiary weight
Strongest available evidence in this index.
Chain of custody
Retail purchase → submitter (ambient, 11 d) → laboratory (hand-carried, 3 d) → assay.
Assay date
16 May 2026
Submitted to the index
04 Jun 2026
Laboratory
Janoshik Analytical, Ostrava, Czechia
Method basis
30 min gradient · high-resolution MS
Verification status
PURITY ONLY
Section 6

Annotations 3

Signed technical comments from index contributors. Not a discussion forum — annotations question or contextualise the result, and the data team replies where a reply is warranted.

dedupe_logic
Two retail purchases of the same lot from different buyers are genuinely independent. Two aliquots of one purchase are not, and the index does not treat them as such.
fill_homogeneity
One vial is one fill event. Three from the same lot would separate fill variability from a systematic offset, and that distinction changes what you do about it.
label_claim
Everything on this record reconciles: gross fill, target content, recovered mass and claim. The gap is explained by the arithmetic rather than left as a discrepancy.
Section 7

Related records

Same batch — lot QSC-2605-A6715 n=10

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-041549QSC-2605-A6715Medutest2026-Q299.934.83Buyer-sourced0PASS
AX-2026-041550QSC-2605-A6715Janoshik2026-Q299.775.00101.8Buyer-sourced0PASS
AX-2026-041551QSC-2605-A6715Janoshik2026-Q299.744.60105.7Buyer-sourced0PASS
AX-2026-041552QSC-2605-A6715VendorInvestigate2026-Q299.704.6996.2Buyer-sourced0PASS
AX-2026-041553QSC-2605-A6715VendorInvestigate2026-Q299.934.9592.4Buyer-sourced0PASS
AX-2026-041554QSC-2605-A6715Kestrel2026-Q299.884.85Buyer-sourced0PASS
AX-2026-041555QSC-2605-A6715PeptideMeter2026-Q299.935.2592.1Buyer-sourced0PASS
AX-2026-041556QSC-2605-A6715PeptideMeter2026-Q299.294.30Buyer-sourced0PASS
AX-2026-041557QSC-2605-A6715Medutest2026-Q299.734.8894.5Buyer-sourced0PASS
Other recent GHRP-6 records in the index.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042012AMBAMB-2603-S5667Janoshik2026-Q399.375.9088.8Laboratory-retained1MARGINAL
AX-2026-042528HJHJ-2603-R5329VendorInvestigate2026-Q398.691.8795.8Buyer-sourced0FAIL
AX-2026-042015AMBAMB-2603-S5667Janoshik2026-Q399.546.4497.1Buyer-sourced0PASS
AX-2026-042526HJHJ-2603-R5329Medutest2026-Q399.373.06Laboratory-retained0PASS
AX-2026-042527HJHJ-2603-R5329VendorInvestigate2026-Q399.212.7793.2Buyer-sourced0PASS
AX-2026-042525HJHJ-2603-R5329Janoshik2026-Q399.523.2492.0Buyer-sourced0PASS
AX-2026-042013AMBAMB-2603-S5667Kestrel2026-Q399.935.75Buyer-sourced0PASS
AX-2026-042017AMBAMB-2603-S5667Medutest2026-Q399.766.4297.4Buyer-sourced0PASS
Other recent QSC records in the index.
ReportCompoundLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-041599CJC-1295 (no DAC)QSC-2606-V7416VendorInvestigate2026-Q397.963.52Buyer-sourced1FAIL
AX-2026-041601CJC-1295 (no DAC)QSC-2606-V7416Kestrel2026-Q398.334.10Buyer-sourced1MARGINAL
AX-2026-041602CJC-1295 (no DAC)QSC-2606-V7416VendorInvestigate2026-Q398.363.38101.8Buyer-sourced1MARGINAL
AX-2026-041477TriptorelinQSC-2607-C5749Nordanalyt2026-Q399.533.42Buyer-sourced0PASS
AX-2026-041600CJC-1295 (no DAC)QSC-2606-V7416Nordanalyt2026-Q397.744.91100.9Buyer-sourced1FAIL
AX-2026-041603CJC-1295 (no DAC)QSC-2606-V7416PeptideMeter2026-Q398.434.20Buyer-sourced1MARGINAL
AX-2026-041606CJC-1295 (no DAC)QSC-2606-V7416Janoshik2026-Q398.033.58Buyer-sourced1MARGINAL
AX-2026-041585LiraglutideQSC-2605-W7381Medutest2026-Q399.595.0992.8Laboratory-retained0PASS