Every named impurity on this record has a mass defect consistent with its structural assignment. That is the check that distinguishes an assignment from a guess.
mass_defect
Mass-defect reasoning for distinguishing plausible from implausible impurity assignments.
Section 1
Contribution
Comments technically on records submitted by others. Annotations are signed and are not moderated for agreement.
Records submitted
0
n=0
Annotations
268
n=268
Median purity submitted
suppressed
n=0
n<3 — see individual records
Suppliers covered
0
n=0
This handle has submitted no records. Annotators comment on other people's submissions and are not required to submit.
Section 2
Annotations
Signed technical comments on records. The index does not moderate annotations for agreement with its own arithmetic, and several of these disagree with it. Where a handle has made the same point on several records, one instance is shown and the rest are reachable from the records themselves.
Identity confirmed, purity 98.37 %, mass balance closed. This record is complete against the index definition of complete and there is nothing outstanding on it.
Before assigning D-carnosine epimer from retention alone, check the mass defect on the impurity peak. Plausible and implausible assignments separate cleanly and the check costs nothing.
Mass defect is where it should be for a peptide of this composition. Nothing in the impurity table has a defect inconsistent with its assignment either.
Before assigning des-Tyr1 (−163 Da) from retention alone, check the mass defect on the impurity peak. Plausible and implausible assignments separate cleanly and the check costs nothing.
Identity confirmed and purity at 98.49 %. The two answer different questions — what it is, and how much else is in it — and a record carrying both is the version worth citing.
Mass-defect reasoning narrows this quickly. Very few plausible modifications of Retatrutide would produce a shift in the direction and magnitude observed, and the ones that would are all in the named-impurity table.
Mass-defect reasoning narrows this quickly. Very few plausible modifications of GHRP-6 would produce a shift in the direction and magnitude observed, and the ones that would are all in the named-impurity table.
The purity, water and counter-ion figures on this record stand regardless of the mass question. Only the identity limb is affected, and the status field says exactly that.
Before assigning truncated (1-12) from retention alone, check the mass defect on the impurity peak. Plausible and implausible assignments separate cleanly and the check costs nothing.
Identity confirmed and purity at 99.93 %. The two answer different questions — what it is, and how much else is in it — and a record carrying both is the version worth citing.
If the assignment is shifted by one charge state the error resolves. Confirm the deconvolution before treating +22.1 ppm as a real discrepancy about the material.
Showing 12 distinct comments of 268 annotations by this handle.